![]() ![]() One study in infants found higher levels of BCM-7 in those fed cow’s milk compared to those who were breastfed. However, studies do not support all of the proposed mechanisms ( 20, 21, 22). In theory, peptides like BCM-7 might play a role in the development of autism. AutismĪutism is a mental condition characterized by poor social interaction and repetitive behavior. Yet, further studies are needed before any firm conclusions can be reached. These results indicate that some children may be sensitive to the A1 beta-casein found in cow’s milk. This condition, known as sleep apnea, is linked to an increased risk of SIDS ( 7). One study found high levels of BCM-7 in the blood of infants who temporarily stopped breathing during sleep. Some researchers have speculated that BCM-7 may be involved in some cases of SIDS ( 19). SIDS is the unexpected death of an infant without an apparent cause ( 18). Sudden infant death syndrome (SIDS) is the most common cause of death in infants under 12 months old. A1 and A2 had similar effects on blood vessel function, blood pressure, blood fats, and inflammatory markers ( 16).Īnother study found no significant differences in the effects of A1 and A2 casein on blood cholesterol ( 17). In one study in 15 adults at high risk of heart disease, no significant adverse effects were observed. So far, two trials have investigated the effects of A1 milk on heart disease risk factors in people ( 16, 17). Still, the human relevance of the results has been debated ( 2). This buildup was much lower when the rabbits consumed A2 beta-casein ( 15).įat accumulation may potentially clog blood vessels and cause heart disease. One test in rabbits showed that A1 beta-casein promoted fat buildup in injured blood vessels. Two observational studies link A1 milk consumption to an increased risk of heart disease ( 6, 11). ![]() So far, no clinical trials in humans have investigated the effect of A1 beta-casein on type 1 diabetes. While some animal studies have found no difference between A1 and A2 beta-casein, others show A1 beta-casein to have either protective or adverse effects on type 1 diabetes ( 10, 12, 13, 14). They cannot prove that A1 beta-casein causes type 1 diabetes - only that those who are getting more of it are at a higher risk. However, these studies are observational. Several studies indicate that drinking A1 milk during childhood increases your risk of type 1 diabetes ( 5, 6, 10, 11). Type 1 diabetes is typically diagnosed in children and characterized by a lack of insulin. ![]() While BCM-7 has been extensively researched, its overall health effects remain unclear. Studies have not found BCM-7 in the blood of healthy adults who drink cow’s milk, but a few tests indicate that BCM-7 may be present in infants ( 7, 8, 9). While BCM-7 may affect your digestive system, it’s still unclear to what extent BCM-7 is absorbed intact into your blood. It’s the reason why some people believe regular milk to be less healthy than A2 milk.Ī few research groups suggest that BCM-7 may be linked to type 1 diabetes, heart disease, infant death, autism, and digestive problems ( 5, 6, 7, 8). Some studies indicate that A2 milk may be the healthier of the two.īeta-casomorphin-7 (BCM-7) is an opioid peptide released during the digestion of A1 beta-casein ( 3, 4). SUMMARYĪ1 and A2 milk contain different types of beta-casein protein. Thus, there is some public and scientific debate over these two types of milk.Ī2 milk is produced and marketed by the A2 Milk Company and contains no A1 beta-casein. Some studies suggest that A1 beta-casein may be harmful and that A2 beta-casein is a safer choice. Regular milk contains both A1 and A2 beta-casein, but A2 milk contains only A2 beta-casein. These include Guernsey, Jersey, Charolais, and Limousin cows ( 1, 2). Milk that is high in A2 beta-casein is mainly found in breeds that originated in the Channel Islands and southern France. These breeds include Holstein, Friesian, Ayrshire, and British Shorthorn. Milk from breeds of cows that originated in northern Europe is generally high in A1 beta-casein. Beta-casein is the second most prevalent and exists in at least 13 different forms ( 1). There are several types of casein in milk. Casein is the largest group of proteins in milk, making up about 80% of total protein content. ![]()
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